Yep sure - I actually have two 6-port cards and 1 12-port card currently, all ports connected to port multipliers.
The 6-port card is this one: Amazon.com: Ableconn PEX-SA156 6-Port SATA 6G PCI Express x4 Host Adapter Card - AHCI 6Gbps SATA III Port-Multiplier PCIe 3.0 4-Lane Low Profile Controller Card (ASMedia ASM1166): Computers & Accessories Looks like it is ASM1166 - works great with all PMs on all ports.
The 12-port card is this one: Chia Mining 12 Port SATA III PCIe Card PCI E SATA Controller Card to 6GB Internal Adapter Converter PCI SATA 3.0 Expansion Cards|Add On Cards| - AliExpress. Looks like this one is ASM1064, also works great with PMs on all ports. When this card boots up, the PC actually recognizes it as two PCIe cards and each goes through its own process of identifying the drives. I’m guessing they have a little PCIe hub on the card so the card is just acting like 2 6-port cards.
Also, I just ordered this 24-port card last week: SATA PCI E Adapter 4/5/8/10/12/16/20/24 Ports PCI Express X1 X4 X8 X16 To SATA 3.0 6Gbp Interface Rate Expansion Card Controller|Computer Cables & Connectors| - AliExpress Will be interested to see if this shows up as four PCIe cards in BIOS - it looks to be ASM1064 and says it does support PMs so hopefully it works!